Background & Aims: Acetaminophen (APAP) overdose is the most common cause of drug-induced liver injury worldwide.Uric acid (UA) is involved in sterile inflammation in many organs, but its role in APAP-induced liver injury remains elusive.Methods: We quantified the concentration of UA in the serum and liver tissues of APAP-overdosed mice and exp
Rural health services, and the workforces that provide those services, are under unprecedented pressure due to insufficient health workforce numbers and distribution of health workforce weighted to urban areas.This creates health service access issues in rural areas, compounding existing health inequalities between rural and urban people.Many appro
Sustainable development represents a new paradigm about the functioning of society, an approach that involves peaceful societies where the benefits are accessible to all.In addition, this context promotes access to justice for all and the creation of effective, accountable, and inclusive institutions at all levels.Analyzing mainly the social dimens
OBJECTIVE: Novel, inexpensive solutions are needed for improved management of vector-borne and other diseases in resource-poor environments.Emerging free software providing access to satellite imagery and simple editing tools (e.g.Google EarthTM) complement existing geographic information system (GIS) software and provide new opportunities for: (i)